Chemical name: 1,4:5,8-Dimethanonaphthalene, 1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-, (1.alpha.,4.alpha.,4a.beta.,5.alpha.,8.alpha.,8a.beta.)- Final regulatory action has been taken for the category: Pesticide Final regulatory action: The chemical is Banned Use or uses prohibited by the final regulatory action: All uses are banned Pesticide use or uses that remain allowed: All uses are banned The final regulatory action was based on a risk or hazard evaluation: Yes Summary of the final regulatory action: The substance is banned by an order of the Ministry of Health of the ex-USSR and by the Ordinance of the Government of the Kyrgyz Republic of 27 June 2001 No. 376. The reasons for the final regulatory action were relevant to: Human health and environment Summary of known hazards and risks to human health: In humans the primary acute toxic effects are on the central nervous system, including hyperexcitability and tremors followed by convulsions and possibly death. The liver is also a target organ. Dieldrin (to which aldrin is rapidly converted after absorption) has been found to cause immunosuppression in mice. Aldrin can be absorbed into the body both through skin contact and inhalation at the manufacturing, formulating and application stages. One or more gross overexposures can lead to acute convulsive intoxication; a greater number of smaller doses may cause accumulative intoxification. A time-weighted average TLV for exposure to aldrin and dieldrin has been set at 0.25 mg/m3. One fatal overexposure of an applicator has been reported. Expected effect of the final regulatory action in relation to human health: Reduction of risks and hazards for humans. Summary of known hazards and risks to the environment: Persistent in the environment, especially in regions with temperate climate. Highly toxic to fish, crustaceans, and many bird and animal species. For fish and crustaceans LC50s are ranging from 2.2 to 53 g/l. Toxicity to fish has been found to vary by species between 6.6 and 520 mg/kg bw. Expected effect of the final regulatory action in relation to the environment: Reduction of risks and hazards for the environment. Date of entry into force of the final regulatory action: 27/07/2001 |